Arndt K A, Jick H
JAMA. 1976 Mar 1;235(9):918-23.
Rates of allergic skin reactions to commonly used drugs were estimated from data obtained on 22,227 consecutively monitored medical inpatients. A total of 57 drugs were implicated with skin reactions. Five or more reactions were attributed to each of 22 drugs (or drug groups). Many commonly used drugs did not appear to cause any allergic reactions. The study provides the practicing physician with drug-specific quantitative data that can be used to evaluate the causes of drug-induced rash, itching, or hives.
根据对22227名连续监测的住院患者所获数据，估算了对常用药物的过敏性皮肤反应发生率。共有57种药物与皮肤反应有关。22种药物（或药物组）中的每一种都导致了5次或更多的反应。许多常用药物似乎不会引起任何过敏反应。该研究为执业医师提供了特定药物的定量数据，可用于评估药物引起的皮疹、瘙痒或荨麻疹的病因。
