Lacroix P, Aboyans V, Preux P M, Houlès M B, Laskar M
Department of Cardiovascular Surgery and Vascular Medicine, CHU Dupuytren, Limoges, France.
Int Angiol. 2003 Jun;22(2):172-6.
A cross sectional study of the prevalence and risk factors of chronic venous insufficiency (CVI) in a South European occupational population was performed.
Over a 7-month period a questionnaire (CVI symptoms, general data and life style habits) was administrated to 1604 consecutive females (73.3%) and 586 consecutive males (26.7%). An oriented clinical examination was then performed. Subjects were classified into 4 groups: asymptomatic, light, moderate and severe CVI. Univariate and multivariate analysis were used.
Mean age 38.8+/-11.6 years (range 15-65). The prevalence of CVI all classes confounded was 51.4% (62.3% in women and 21.8% in men); the prevalence of moderate and severe CVI was 10.4% (12.1% in female and 6.3% in male). Age (Odds Ratio (OR): 1.93, 95% confidence interval (CI): 1.55-3.53), female sex (OR: 2.34, 95% CI: 1.62-2.30), obesity (kg/m(2)) (OR:1.11, 95% CI: 1.07-1.15) and familial history of CVI (OR: 2.80, 95% CI: 2.02-3.89) were risks factors of moderate and severe CVI. The comparison extended to the whole group of CVI added other risk factors: history of leg injury, pregnancy; a sitting posture at work. Unexpectedly smoking had a protective effect but only in the female group for the last one.
CVI is an important medical problem concern in this population. Some of the risk factors like obesity and standing position at work may benefit from preventive measures.
对南欧职业人群慢性静脉功能不全（CVI）的患病率及危险因素进行横断面研究。
在7个月的时间里，对1604名连续的女性（73.3%）和586名连续的男性（26.7%）进行问卷调查（CVI症状、一般资料和生活方式习惯）。然后进行定向临床检查。受试者被分为4组：无症状、轻度、中度和重度CVI。采用单因素和多因素分析。
平均年龄38.8±11.6岁（范围15 - 65岁）。所有类别混淆的CVI患病率为51.4%（女性为62.3%，男性为21.8%）；中度和重度CVI的患病率为10.4%（女性为12.1%，男性为6.3%）。年龄（比值比（OR）：1.93，95%置信区间（CI）：1.55 - 3.53）、女性性别（OR：2.34，95% CI：1.62 - 2.30）、肥胖（kg/m²）（OR：1.11，95% CI：1.07 - 1.15）和CVI家族史（OR：2.80，95% CI：2.02 - 3.89）是中度和重度CVI的危险因素。扩展到整个CVI组的比较增加了其他危险因素：腿部受伤史、怀孕；工作时的坐姿。出乎意料的是，吸烟有保护作用，但仅在女性组中对最后一项有保护作用。
CVI是该人群中一个重要的医学问题。肥胖和工作时站立姿势等一些危险因素可能受益于预防措施。
