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髂静脉支架置入术治疗流出道梗阻对严重慢性静脉功能不全患者的生活质量没有显著影响。

Iliac venous stenting for outflow obstruction does not significantly change the quality of life of patients with severe chronic venous insufficiency.

作者信息

Shiferson Alexander, Aboian Edouard, Shih Michael, Pu Qinghua, Jacob Theresa, Rhee Robert Y

机构信息

Department of Surgery, Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

JRSM Cardiovasc Dis. 2019 Nov 26;8:2048004019890968. doi: 10.1177/2048004019890968. eCollection 2019 Jan-Dec.

Abstract

PURPOSE

Percutaneous endovenous iliac stenting has emerged as a new modality in the treatment of advanced chronic venous insufficiency with outflow obstruction. However, the effect of this intervention on the quality of life remains unclear. We examined the impact of iliac venous stenting for outflow obstruction as compared to conservative medical management on the quality of life in severe chronic venous insufficiency patients.

METHODS

Medical records of all patients with CEAP class 5 and 6 disease (N = 172) who underwent ilio-caval venography with intravascular ultrasonography (IVUS) at a single institution over a seven-year period, were reviewed for this case-control study. Quality of life evaluation was performed utilizing the Chronic Venous Insufficiency Quality of Life Questionnaire (CIVIQ-20) one year after the index procedure.

RESULTS

Of the 172 severe chronic venous insufficiency patients, 109 were stented and 63 patients were treated medically based on their venography and IVUS results. The indication for stenting was confirmation of IVUS determined surface area or diameter outflow stenosis of greater than 50% within the common or external iliac venous systems. Eighty patients (47%) responded with completed CIVIQ-20 questionnaires for analysis. Of these, 47 were from the stented group and 33 from the non-stented group. At least moderate persistent pain or discomfort post-procedure was reported by 20 (43%) stented group patients and 19 (58%) non-stented group patients. Scores for all the other criteria in the CIVIQ-20 were similar between the groups. The mean total CIVIQ-20 score was 45.23 and 47.13, respectively, in stented group and non-stented group patients. ( = 0.678).

CONCLUSION

There was no significant difference in the quality of life reported by CEAP 5 and 6 patients who underwent iliac venous stenting versus those who were treated medically for presumed iliac outflow obstruction. Prospective studies are needed to determine the true value of iliac venous stenting based on IVUS criteria in the management advanced chronic venous insufficiency.

摘要

目的

经皮髂静脉支架置入术已成为治疗伴有流出道梗阻的晚期慢性静脉功能不全的一种新方法。然而,这种干预对生活质量的影响仍不明确。我们比较了髂静脉支架置入术治疗流出道梗阻与保守药物治疗对严重慢性静脉功能不全患者生活质量的影响。

方法

回顾了在一家机构进行了七年的所有CEAP 5级和6级疾病患者(N = 172)的病历,这些患者接受了髂股静脉造影和血管内超声检查(IVUS),用于本病例对照研究。在索引手术一年后,使用慢性静脉功能不全生活质量问卷(CIVIQ - 20)进行生活质量评估。

结果

在172例严重慢性静脉功能不全患者中,109例接受了支架置入术,63例根据其静脉造影和IVUS结果接受了药物治疗。支架置入的指征是IVUS确定髂总静脉或髂外静脉系统内表面积或直径流出道狭窄大于50%。80例患者(47%)回复了完整的CIVIQ - 20问卷以供分析。其中,47例来自支架置入组,33例来自非支架置入组。支架置入组20例(43%)患者和非支架置入组19例(58%)患者报告术后至少有中度持续性疼痛或不适。两组在CIVIQ - 20中所有其他标准的得分相似。支架置入组和非支架置入组患者的CIVIQ - 20总平均得分分别为45.23和47.13(P = 0.678)。

结论

接受髂静脉支架置入术的CEAP 5级和6级患者与因假定的髂静脉流出道梗阻接受药物治疗的患者报告的生活质量没有显著差异。需要进行前瞻性研究以确定基于IVUS标准的髂静脉支架置入术在治疗晚期慢性静脉功能不全中的真正价值。

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