Baron Jeffrey, Alexander Tim
Department of Radiology, University of Alberta, 8440-112 St., Edmonton AB T6G 2B7.
Can Assoc Radiol J. 2003 Jun;54(3):152-4.
To determine if the viscosity of thickened juice mixtures used in modified barium swallow studies significantly changes with the addition of powdered barium. We also describe a test formulation created using liquid barium, which has a negligible effect on juice viscosity.
The viscosities of water and standardized honey- and nectar-consistency juices mixed with different amounts of powdered barium were measured by timing the laminar flow of a given initial hydrostatic head of fluid under gravity though an orifice of fixed diameter. Standardized juices were then mixed with a liquid formulation of barium and with measured quantities of water to produce viscosities that more closely equated with those of the standardized juices.
With the addition of powdered barium, viscosity increased in all fluids, most markedly with the nectar-consistency juice. Liquid barium formulations maintained the viscosities of the original thickened juices.
Rendering juices radio-opaque with barium powder results in dramatic increases in the viscosity of the resulting mixture and compromises diagnostic accuracy. Liquid barium preparations have the advantage that they can be rapidly and accurately dispensed by syringe, and their use does not significantly increase the viscosity of the preparation.
确定改良钡餐吞咽研究中使用的增稠果汁混合物的粘度在添加钡粉后是否会显著变化。我们还描述了一种使用液体钡创建的测试配方，其对果汁粘度的影响可忽略不计。
通过计时在重力作用下给定初始静水头的流体通过固定直径孔口的层流，测量与不同量钡粉混合的水以及标准化蜂蜜和花蜜稠度果汁的粘度。然后将标准化果汁与钡的液体制剂以及测量量的水混合，以产生与标准化果汁更接近的粘度。
添加钡粉后，所有流体的粘度均增加，花蜜稠度果汁的粘度增加最为明显。液体钡制剂保持了原始增稠果汁的粘度。
用钡粉使果汁具有放射性不透明性会导致所得混合物的粘度急剧增加，并损害诊断准确性。液体钡制剂的优点是可以通过注射器快速准确地给药，并且其使用不会显著增加制剂的粘度。
