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柯氏叶下珠中毒:病例报告及文献综述

Cleistanthus collinus poisoning: case reports and review of the literature.

作者信息

Eswarappa Shashiraj, Chakraborty Amiya Ranjan, Palatty Babu Urumese, Vasnaik Mabel

机构信息

Department of Emergency Medicine, St. John's Medical College Hospital, Bangalore, India.

出版信息

J Toxicol Clin Toxicol. 2003;41(4):369-72. doi: 10.1081/clt-120022005.

DOI:10.1081/clt-120022005
PMID:12870879
Abstract

We report the cases of two previously healthy young patients who ingested the liquid extracted from the crushed leaves of Cleistanthus collinus (Family: Euphorbiaceae) in an attempt to commit suicide. Both patients developed life threatening complications such as hypokalemia, hypotension, cardiac arrhythmias, neuromuscular weakness, respiratory failure, and renal failure following a transient quiescent period of up to 4 days. Other significant findings noted include leucocytosis, coagulopathy, elevated liver enzymes, hyperchloremic metabolic acidosis, and an alkaline urinary pH. Both patients received supportive care as no specific antidote was available, and ultimately died. We have reviewed the published literature on C. collinus poisoning.

摘要

我们报告了两名既往健康的年轻患者的病例,他们为自杀而摄入了从黑面神(大戟科)碾碎的叶子中提取的液体。两名患者在长达4天的短暂静止期后,均出现了危及生命的并发症,如低钾血症、低血压、心律失常、神经肌肉无力、呼吸衰竭和肾衰竭。其他显著发现包括白细胞增多、凝血病、肝酶升高、高氯性代谢性酸中毒以及尿液pH值呈碱性。由于没有特效解毒剂,两名患者均接受了支持性治疗,最终死亡。我们回顾了已发表的关于黑面神中毒的文献。

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