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中毒:一例故意中毒的病例报告。

poisoning: a case report of intentional poisoning.

作者信息

Bompelli Nandakishore, Reddy C Rakesh, Modani Santosh, Deshpande Anirudda

机构信息

Internal Medicine, Aditya Hospital, Warangal, Telangana, India.

Medicine, Aditya Hospital, Warangal, Warangal, India.

出版信息

BMJ Case Rep. 2019 Feb 9;12(2):e228197. doi: 10.1136/bcr-2018-228197.

Abstract

We report a case of 50-year-old male patient from tribal area in South Indian state of Telangana, who ingested the liquid extract from crushed leaves of the plant, cleistanthus collinius with the intention of self-harm. Immediate gastric lavage and activated charcoal administration was done and the patient was subsequently admitted into an acute medical care unit. During first 24 hours of monitoring, the patient was clinically stable. There was mild normal anion gap metabolic acidosis and hypokalaemia on arterial blood gas (ABG) and was corrected accordingly. On second day of admission he developed acute onset shortness of breath. Chest auscultation revealed extensive bilateral coarse crackles. Chest X-ray was suggestive of acute respiratory distress syndrome (ARDS). The patient had to be intubated. Continuous renal replacement therapy (CRRT) was initiated in view of worsening metabolic acidosis and unstable haemodynamics. In spite of appropriate intensive care measures, the patient succumbed to illness. Immediate gastric lavage and activated charcoal administration was done and the patient was subsequently admitted into an acute medical care unit. During first 24 hours of monitoring, the patient was clinically stable. There was mild normal anion gap metabolic acidosis and hypokalaemia on ABG and was corrected accordingly. On second day of admission, he developed acute onset shortness of breath. Chest auscultation revealed extensive bilateral coarse crackles. Chest X-ray was suggestive of ARDS. The patient had to be intubated on day 2. CRRT was initiated in view of worsening metabolic acidosis and unstable haemodynamics. In spite of appropriate intensive care measures, the patient gradually deteriorated, had cardiac arrest and passed away on day 5 of his hospital stay.

摘要

我们报告了一例来自印度南部特伦甘纳邦部落地区的50岁男性患者,他为了自杀而摄入了植物克利须那藤(Cleistanthus collinus)碾碎叶子的液体提取物。立即进行了洗胃和给予活性炭,随后患者被收治入急性医疗护理单元。在监测的最初24小时内,患者临床情况稳定。动脉血气分析(ABG)显示有轻度正常阴离子间隙代谢性酸中毒和低钾血症,并相应地进行了纠正。入院第二天,他突然出现呼吸急促。胸部听诊发现双侧广泛的粗湿啰音。胸部X线提示急性呼吸窘迫综合征(ARDS)。患者不得不进行气管插管。鉴于代谢性酸中毒恶化和血流动力学不稳定,启动了持续肾脏替代疗法(CRRT)。尽管采取了适当的重症监护措施,患者仍因病死亡。立即进行了洗胃和给予活性炭,随后患者被收治入急性医疗护理单元。在监测的最初24小时内,患者临床情况稳定。ABG显示有轻度正常阴离子间隙代谢性酸中毒和低钾血症,并相应地进行了纠正。入院第二天,他突然出现呼吸急促。胸部听诊发现双侧广泛的粗湿啰音。胸部X线提示ARDS。患者在第二天不得不进行气管插管。鉴于代谢性酸中毒恶化和血流动力学不稳定,启动了CRRT。尽管采取了适当的重症监护措施,患者病情逐渐恶化,发生心脏骤停,并在住院第5天死亡。

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本文引用的文献

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Cleistanthus collinus poisoning.柯里大戟中毒
J Assoc Physicians India. 2006 Sep;54:742-4.
8
Arylnaphthalide lignans from Cleistanthus collinus.来自棒柄花的芳基萘类木脂素。
Chem Pharm Bull (Tokyo). 2003 Nov;51(11):1299-300. doi: 10.1248/cpb.51.1299.
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Oduvanthalai leaf poisoning.奥杜万塔莱叶中毒
J Assoc Physicians India. 1987 Nov;35(11):769-71.

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