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蛋白质组学标准计划

The proteomics standards initiative.

作者信息

Orchard Sandra, Hermjakob Henning, Apweiler Rolf

机构信息

EMBL Outstation, European Bioinformatics Institute, Wellcome Trust, Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Proteomics. 2003 Jul;3(7):1374-6. doi: 10.1002/pmic.200300496.

Abstract

The Proteomics Standards Initiative (PSI) aims to define community standards for data representation in proteomics and to facilitate data comparison, exchange and verification. Progress has been made in the development of common standards for data exchange in the fields of both mass spectrometry and protein-protein interaction. A proteomics-specific extension is being created for the emerging American Society for Tests and Measurements mass spectrometry standard, which will be supported by manufacturers of both hardware and software. A data model for proteomics experimentation is under development and discussions on a public repository for published proteomics data are underway. The Protein-Protein Interactions group expects to publish the Level 1 PSI data exchange format for protein-protein interactions soon and discussions as to the content of Level 2 have been initiated.

摘要

蛋白质组学标准计划(PSI)旨在定义蛋白质组学数据表示的社区标准,并促进数据比较、交换和验证。在质谱分析和蛋白质-蛋白质相互作用领域,数据交换通用标准的制定已取得进展。正在为新兴的美国试验与材料协会质谱分析标准创建特定于蛋白质组学的扩展,该扩展将得到硬件和软件制造商的支持。蛋白质组学实验的数据模型正在开发中,关于已发表蛋白质组学数据公共储存库的讨论也在进行中。蛋白质-蛋白质相互作用小组预计很快会发布蛋白质-蛋白质相互作用的PSI 1级数据交换格式,并且已经开始了关于2级内容的讨论。

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