中国农村地区精神分裂症的患病率及病程
Prevalence and course of schizophrenia in a Chinese rural area.
作者信息
Ran Mao-Sheng, Xiang Meng-Ze, Li Sheng-Xian, Shan You-He, Huang Ming-Sheng, Li Si-Gan, Liu Zhong-Ren, Chen Eric Yu-Hai, Chan Cecilia Lai-Wan
机构信息
Institute of Mental Health, West China Hospital, West China Medical School of Sichuan University, Chengdu.
出版信息
Aust N Z J Psychiatry. 2003 Aug;37(4):452-7. doi: 10.1046/j.1440-1614.2003.01203.x.
OBJECTIVE
To assess the characteristics and factors affecting course of schizophrenia in a Chinese rural area.
METHOD
An epidemiological investigation was conducted to identify all the patients with schizophrenia among 149 231 people in Xinjin County, Chengdu.
RESULTS
The total prevalence of schizophrenia was 4.13 per 1000 population. Males had an earlier mean age of onset (29.6 years) than females (32.3 years). Duration of illness before treatment and the total duration of illness were found to be significantly associated with level of remission. The status of treatment, family economy, housing, and families' care of patients had a significant effect on the clinical course of the illness.
CONCLUSIONS
Duration of illness before treatment may be an important predictor of course in schizophrenia. Early treatment for the patients may produce higher level of improvement in prognosis. Education intervention and community-based service are urgent priorities for these patients.
目的
评估中国农村地区精神分裂症的特征及影响病程的因素。
方法
开展一项流行病学调查，在成都市新津县的149231人中识别出所有精神分裂症患者。
结果
精神分裂症的总患病率为每1000人中有4.13人。男性的平均发病年龄（29.6岁）早于女性（32.3岁）。发现治疗前病程及总病程与缓解程度显著相关。治疗状况、家庭经济、住房以及家庭对患者的照料对疾病的临床病程有显著影响。
结论
治疗前病程可能是精神分裂症病程的重要预测指标。对患者进行早期治疗可能会使预后有更高水平的改善。教育干预和社区服务是这些患者的当务之急。
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