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中文成年人精神分裂症谱系、情感性及其他非情感性精神病障碍的终生患病率及其相关因素。

Lifetime Prevalence and Correlates of Schizophrenia-Spectrum, Affective, and Other Non-affective Psychotic Disorders in the Chinese Adult Population.

机构信息

Department of Psychiatry, the University of Hong Kong, Hong Kong.

State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong.

出版信息

Schizophr Bull. 2017 Oct 21;43(6):1280-1290. doi: 10.1093/schbul/sbx056.

Abstract

Lifetime prevalence of psychotic disorders varies widely across studies. Epidemiological surveys have rarely examined prevalences of specific psychotic disorders other than schizophrenia, and the majority used a single-phase design without employing clinical reappraisal interview for diagnostic verification. The current study investigated lifetime prevalence, correlates and service utilization of schizophrenia-spectrum, affective, and other non-affective psychotic disorders in a representative sample of community-dwelling Chinese adult population aged 16-75 years (N = 5719) based on a territory-wide, population-based household survey for mental disorders in Hong Kong. The survey adopted a 2-phase design comprising first-phase psychosis screening and second-phase diagnostic verification incorporating clinical information from psychiatrist-administered semi-structured interview and medical record review to ascertain DSM-IV lifetime diagnosis for psychotic disorders. Data on sociodemographics, psychosocial characteristics and service utilization were collected. Our results showed that lifetime prevalence was 2.47% for psychotic disorder overall, 1.25% for schizophrenia, 0.15% for delusional disorder, 0.38% for psychotic disorder not otherwise specified, 0.31% for bipolar disorder with psychosis, and 0.33% for depressive disorder with psychosis. Schizophrenia-spectrum disorder was associated with family history of psychosis, cigarette smoking and variables indicating socioeconomic disadvantage. Victimization experiences were significantly related to affective psychoses and other non-affective psychoses. Around 80% of participants with any psychotic disorder sought some kind of professional help for mental health problems in the past year. Using comprehensive diagnostic assessment involving interview and record data, our results indicate that approximately 2.5% of Chinese adult population had lifetime psychotic disorder which represents a major public health concern.

摘要

终生患病率的精神障碍在不同的研究中差异很大。流行病学调查很少检查特定的精神障碍患病率除了精神分裂症,和大多数使用单相设计不采用临床再评估面试诊断验证。本研究调查了终生患病率,相关性和服务利用的精神分裂症谱系,情感障碍和其他非情感性精神障碍在一个代表性的样本中社区居住的中国成年人口年龄在 16-75 岁(N = 5719)基于一个全港,基于人群的家庭调查精神障碍在香港。该调查采用了两阶段设计,包括第一阶段的精神病筛查和第二阶段的诊断验证,纳入了来自精神科医生管理的半结构化访谈和病历回顾的临床信息,以确定 DSM-IV 终生诊断为精神障碍。收集了社会人口统计学、心理社会特征和服务利用的数据。我们的结果显示,终生患病率为 2.47%的精神障碍,1.25%的精神分裂症,0.15%的妄想障碍,0.38%的未特定的精神病,0.31%的伴有精神病的双相情感障碍,0.33%的伴有精神病的抑郁障碍。精神分裂症谱系障碍与精神病家族史、吸烟和社会经济劣势的变量有关。受害经历与情感性精神病和其他非情感性精神病显著相关。大约 80%的任何精神障碍患者在过去一年中因心理健康问题寻求过某种专业帮助。使用包括访谈和记录数据的综合诊断评估,我们的结果表明,大约 2.5%的中国成年人口有终生精神障碍,这是一个主要的公共卫生问题。

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