高龄孕妇基因终止妊娠后的生殖行为及产前诊断

Reproductive behaviour and prenatal diagnosis following genetic termination of pregnancy in women of advanced maternal age.

作者信息

Brandenburg H, De Koning W, Jahoda M G, Stijnen T, De Ridder M A, Sachs E S, Wladimiroff J W

机构信息

Department of Obstetrics and Gynaecology, Academic Hospital Rotterdam-Dijkzigt, Erasmus University, The Netherlands.

出版信息

Prenat Diagn. 1992 Dec;12(12):1031-5. doi: 10.1002/pd.1970121208.

DOI:10.1002/pd.1970121208

PMID:1287638

Abstract

One hundred and fifty-one women of advanced maternal age who underwent genetic termination of pregnancy (TOP) were studied for their reproductive behaviour and the type of procedure for prenatal diagnosis in a subsequent pregnancy. A total of 59 women (39 per cent) had a further pregnancy. In all continuing pregnancies prenatal diagnosis was performed, of which 75 per cent consisted of chorionic villus sampling (CVS). Reproductive behaviour following a genetic termination was negatively correlated with maternal age and parity. Both reproductive behaviour and the choice to undergo a diagnostic procedure in the next pregnancy were independent of the type of diagnostic procedure in the previous affected pregnancy.

摘要

对151名高龄产妇进行了研究，她们均接受了妊娠基因终止（TOP），研究内容包括她们的生殖行为以及后续妊娠中的产前诊断程序类型。共有59名女性（39%）再次怀孕。在所有继续妊娠的情况下都进行了产前诊断，其中75%采用绒毛取样（CVS）。基因终止妊娠后的生殖行为与产妇年龄和胎次呈负相关。生殖行为以及下次妊娠中接受诊断程序的选择均与先前受影响妊娠的诊断程序类型无关。