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巴氯芬泵导管微骨折伴间歇性剂量不足和过量。

Microfracture of a baclofen pump catheter with intermittent under- and overdose.

作者信息

Dawes William J, Drake James M, Fehlings Darcy

机构信息

Department of Neurosurgery, Hospital for Sick Children, and Bloorview-MacMillan Rehabilitation Center, Toronto, Canada.

出版信息

Pediatr Neurosurg. 2003 Sep;39(3):144-8. doi: 10.1159/000071652.

DOI:10.1159/000071652
PMID:12876394
Abstract

An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of x20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means.

摘要

一名植入鞘内巴氯芬泵的8岁男孩出现巴氯芬剂量不足和过量的间歇性症状。对泵进行询问、测量泵的容量、拍摄普通X光片、进行导管造影荧光检查以及对鞘内导管尖端进行CT扫描,结果均无异常。仅在20倍放大倍数下才发现硬膜外导管有微骨折,扫描电子显微镜检查证实了这一点。更换导管后症状缓解。巴氯芬泵系统的鞘内导管微骨折可能会出现令人困惑的症状,并且难以通过传统方法诊断。

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