Paulus Martin P, Frank Lawrence R
Laboratory of Biological Dynamics and Theoretical Medicine, University of California San Diego, La Jolla, CA 92093-0603, USA.
Neuroreport. 2003 Jul 18;14(10):1311-5. doi: 10.1097/01.wnr.0000078543.07662.02.
Preference judgment, the process of selecting a response from several alternatives based on which alternative the subject likes best, is an important aspect of daily life. The current study examined whether neural substrates that are thought to be critical for generating somatic markers are involved in preference judgments. Fifteen healthy, right-handed subjects performed a preference judgment task during functional magnetic resonance imaging. The medial frontal gyrus was significantly more activated during the preference judgment trials, relative to visual discrimination trials. Other areas that were also differentially activated included the posterior parietal cortex, the anterior cingulate and the left anterior insula. These findings are consistent with the role of the ventromedial prefrontal cortex in the representation of complex appetitive states.
偏好判断是日常生活的一个重要方面，它是指个体基于自身最喜欢的选项，从多个备选方案中选择一个反应的过程。当前的研究探讨了那些被认为对产生躯体标记至关重要的神经基质是否参与了偏好判断。15名健康的右利手受试者在功能磁共振成像过程中执行了一项偏好判断任务。与视觉辨别试验相比，在偏好判断试验期间，内侧前额叶回的激活明显更强。其他也有差异激活的区域包括顶叶后皮质、前扣带回和左侧前岛叶。这些发现与腹内侧前额叶皮质在表征复杂的欲望状态中的作用是一致的。
