Zádori J, Kozinszky Z, Orvos H, Katona M, Pál A, Kovács L
Center for Assisted Reproduction, Kaáli Institute, Szeged, Hungary.
J Assist Reprod Genet. 2003 Jun;20(6):216-21. doi: 10.1023/a:1024103427374.
To determine the rates of pregnancy complications following in vitro fertilization in comparison with those in a matched control group.
A total of 13,543 deliveries at the Department of Obstetrics and Gynecology, University of Szeged, between January 1, 1995 and February 28, 2002 were subjected to retrospective analysis The 230 (1.7%) pregnancies following IVF-ET were evaluated and matched with spontaneous pregnancies concerning age, parity, gravidity, and previous obstetric outcome. Demographic and selected maternal characteristics, pregnancy and labor complications, and neonatal outcome were compared in the two groups
The pregnancy complication rate was partly significantly higher among the singleton IVF-ET pregnancies. The obstetric risk was elevated, though not significantly concerning twin pregnancies.
IVF-ET presents an additional obstetric risk. The neonatal outcome displays a significant difference only concerning an increased premature birth rate of singleton pregnancies. Triplet IVF-ET pregnancies involve a much higher risk of both pregnancy complications and neonatal outcome.
确定体外受精后妊娠并发症的发生率，并与匹配的对照组进行比较。
对1995年1月1日至2002年2月28日在塞格德大学妇产科的13543例分娩进行回顾性分析。对230例（1.7%）体外受精-胚胎移植后的妊娠进行评估，并在年龄、产次、妊娠次数和既往产科结局方面与自然妊娠进行匹配。比较两组的人口统计学和选定的母亲特征、妊娠和分娩并发症以及新生儿结局。
单胎体外受精-胚胎移植妊娠的妊娠并发症发生率部分显著较高。产科风险有所升高，尽管双胎妊娠的升高不显著。
体外受精-胚胎移植存在额外的产科风险。新生儿结局仅在单胎妊娠早产率增加方面显示出显著差异。三胎体外受精-胚胎移植妊娠在妊娠并发症和新生儿结局方面都涉及更高的风险。
