45例严重急性呼吸综合征患者的临床分析
Clinical analysis of 45 patients with severe acute respiratory syndrome.
作者信息
Xue Xiaoyan, Gao Zhancheng, Xu Yu, Ding Xiulan, Yuan Liping, Li Wenjuan, Zhu Jihong
机构信息
Department of Emergency Medicine, Peking University People's Hospital, Beijing 100044, China.
出版信息
Chin Med J (Engl). 2003 Jun;116(6):819-22.
OBJECTIVE
To explore the clinical and radiological features of severe acute respiratory syndrome (SARS).
METHODS
Analysis of the clinical presentation, chest radiographs, course of disease and features of severe pneumonia in 45 SARS patients diagnosed at our hospital in Beijing between April 5 - 20, 2003. Also included is a summation of the clinical features of SARS.
RESULTS
(1) SARS appears to have high infectivity; (2) the most common symptom is fever; (3) the count of leukocyte is normal or decreased; (4) most patients (35/45, 77.8%) had experienced a 24-hour fever prior to the abnormal chest X-ray changes which showed progression of pulmonary infiltrates within 48 hours in 71.1% (32/45) of the patients and, (5) the percentage of patients who developed severe pneumonia (24.4%) is higher than those who developed typical pneumonia.
CONCLUSION
SARS is a disease with high infectivity and has its own clinical and radiological features. Early recognition, prompt isolation, and appropriate therapy are the key to combat this infection.
目的
探讨严重急性呼吸综合征（SARS）的临床及影像学特征。
方法
对2003年4月5日至20日在北京我院确诊的45例SARS患者的临床表现、胸部X线片、病程及重症肺炎特征进行分析。还包括SARS临床特征的总结。
结果
（1）SARS似乎具有高传染性；（2）最常见症状为发热；（3）白细胞计数正常或降低；（4）大多数患者（35/45，77.8%）在胸部X线出现异常改变之前已发热24小时，71.1%（32/45）的患者肺部浸润在48小时内进展，且（5）发生重症肺炎的患者比例（24.4%）高于发生典型肺炎的患者。
结论
SARS是一种具有高传染性的疾病，有其自身的临床及影像学特征。早期识别、及时隔离及恰当治疗是对抗这种感染的关键。
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