Peleman Johan D, van der Voort Jeroen Rouppe
Keygene N.V. Business Unit Genetics, PO Box 216, 6700 AE Wageningen, The Netherlands.
Trends Plant Sci. 2003 Jul;8(7):330-4. doi: 10.1016/S1360-1385(03)00134-1.
Breeding by Design is a concept that aims to control all allelic variation for all genes of agronomic importance. This concept can be achieved through a combination of precise genetic mapping, high-resolution chromosome haplotyping and extensive phenotyping. Thanks to marker technology, software tools and the know-how available today, this goal can now be achieved. Depending on the crop-specific generation time, controlled marker-assisted selection strategies could lead to the production of superior varieties within five to ten years.
设计育种是一个旨在控制所有具有农艺重要性的基因的所有等位基因变异的概念。这一概念可以通过精确的遗传图谱绘制、高分辨率染色体单倍型分析和广泛的表型分析相结合来实现。得益于如今可用的标记技术、软件工具和专业知识,现在可以实现这一目标。根据特定作物的世代时间,可控的标记辅助选择策略可能会在五到十年内培育出优良品种。