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成人大脑中中风后的可塑性重组。

Post-stroke plastic reorganisation in the adult brain.

作者信息

Rossini Paolo M, Calautti Cinzia, Pauri Flavia, Baron Jean-Claude

机构信息

University Campus Bio-Medico, Rome, Italy.

出版信息

Lancet Neurol. 2003 Aug;2(8):493-502. doi: 10.1016/s1474-4422(03)00485-x.

DOI:10.1016/s1474-4422(03)00485-x
PMID:12878437
Abstract

Recovery of function after a stroke is attributable to several factors, including events in the first few days (eg, reabsorption of perilesional oedema, tissue reperfusion). However, consistent reorganisation and recovery after a stroke takes weeks or months. In the early stages, recovery from stroke can vary greatly among patients with identical clinical symptoms. Neuroimaging techniques that enable us to assess baseline and task-related functions, and neurophysiological techniques that measure brain function in "real time", can be used to study the recovery of brain lesions after a stroke. In this review, we discuss important neuroimaging and neurophysiological studies of post-stroke brain reorganisation.

摘要

中风后功能的恢复归因于多种因素,包括最初几天发生的事件(例如,病灶周围水肿的重吸收、组织再灌注)。然而,中风后持续的重组和恢复需要数周或数月时间。在早期阶段,具有相同临床症状的患者中风后的恢复情况可能差异很大。能够评估基线功能和与任务相关功能的神经成像技术,以及“实时”测量脑功能的神经生理学技术,可用于研究中风后脑损伤的恢复情况。在本综述中,我们讨论了中风后脑重组的重要神经成像和神经生理学研究。

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