Suissa Samy
McGill Univerisity, Montreal, Canada.
Pain Res Manag. 2003 Summer;8(2):69-75. doi: 10.1155/2003/235683.
Whiplash, a common injury following motor vehicle crashes, is associated with high costs and a prognosis that is variable and difficult to predict. In this paper, we review findings from the Quebec cohort epidemiological study on predictive factors of recovery from whiplash injury after a motor vehicle crash. We formed a population-based incident cohort of all 4,759 individuals who sustained a whiplash injury resulting from a motor vehicle crash in the province of Québec, Canada, in 1987, and followed these patients for up to seven years. The data were obtained from the universal automobile insurance plan (SAAQ) that covers all seven million residents of the Province for all vehicular-related injuries. From this cohort, we formed the cohort of 3,014 for whom a police report was completed. For this cohort, we obtained data on crash-related factors directly from the police report. We also formed the cohort of 2,627 subjects who had strictly a whiplash injury, without associated injuries. For this cohort, the data on signs and symptoms were obtained from the medical charts kept by the SAAQ. For both cohorts, data on the outcome, the recovery time from whiplash, was obtained from the SAAQ databases. The crash-related cohort study found that socio-demographic factors associated with a longer recovery from whiplash include older age, female sex, having dependents and not being employed full time and that each decreases the rate of recovery by 14 to 16 per cent. Factors related to the crash conditions indicate that being in a truck or bus, with a decrease of 52% in the rate of recovery, being a passenger in the vehicle (15%), colliding with a moving vehicle (16%), and a side or frontal collision (15%) all decrease the rate of recovery. We introduce a combined risk score that predicts longer recovery. In the cohort of subjects with signs and symptoms, the median recovery time was 32 days and 12% of subjects had still not recovered after 6 months. The signs and symptoms that were found to be independently associated with a slower recovery from whiplash, besides female gender and older age, were neck pain on palpation; muscle pain; pain or numbness radiating from neck to arms, hands or shoulders; and headache. Together, the presence of all these factors in females aged 60 predicted a median recovery time of 262 days, compared with 17 days for younger males aged 20 who do not have any of these factors. In contrast, using the Quebec classification of signs and symptoms, the median recovery time varied from 17 to 123 days. We conclude that several socio-demographic and crash-related factors, as well as several signs and symptoms, including a combination of specific musculoskeletal and neurological ones that whiplash patients present with, are predictive of a longer recovery period. These patients should be targeted for an early intervention programme aimed at managing whiplash patients with a poor prognosis.
挥鞭样损伤是机动车碰撞事故后常见的一种损伤,其成本高昂,预后情况多变且难以预测。在本文中,我们回顾了魁北克队列流行病学研究中关于机动车碰撞事故后挥鞭样损伤恢复的预测因素的研究结果。我们以人群为基础,构建了一个事件队列,纳入了1987年在加拿大魁北克省因机动车碰撞事故而遭受挥鞭样损伤的所有4759名个体,并对这些患者进行了长达七年的随访。数据来自覆盖该省所有700万居民的所有与车辆相关损伤的通用汽车保险计划(SAAQ)。从这个队列中,我们形成了有警方报告的3014人的队列。对于这个队列,我们直接从警方报告中获取了与碰撞相关因素的数据。我们还形成了2627名仅患有挥鞭样损伤且无相关联损伤的受试者队列。对于这个队列,体征和症状的数据来自SAAQ保存的病历。对于这两个队列,关于结果,即挥鞭样损伤恢复时间的数据,均从SAAQ数据库中获取。与碰撞相关的队列研究发现,与挥鞭样损伤恢复时间较长相关的社会人口统计学因素包括年龄较大、女性、有受抚养人以及非全职工作,且每一项因素都会使恢复率降低14%至16%。与碰撞情况相关的因素表明,乘坐卡车或公交车会使恢复率降低52%,作为车辆乘客(降低15%)、与行驶中的车辆相撞(降低16%)以及侧面或正面碰撞(降低15%)都会降低恢复率。我们引入了一个综合风险评分来预测恢复时间较长的情况。在有体征和症状的受试者队列中,恢复时间的中位数为32天,12%的受试者在6个月后仍未恢复。除了女性性别和年龄较大外,被发现与挥鞭样损伤恢复较慢独立相关的体征和症状有触诊时颈部疼痛、肌肉疼痛、从颈部向手臂、手部或肩部放射的疼痛或麻木以及头痛。总体而言,60岁女性若存在所有这些因素,预测恢复时间中位数为262天,而没有任何这些因素的20岁年轻男性的恢复时间中位数为17天。相比之下,根据魁北克体征和症状分类,恢复时间中位数从17天到123天不等。我们得出结论,一些社会人口统计学和与碰撞相关的因素,以及一些体征和症状,包括挥鞭样损伤患者出现的特定肌肉骨骼和神经方面的综合症状,都可预测恢复时间较长。这些患者应成为旨在管理预后不良的挥鞭样损伤患者的早期干预计划的目标对象。