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黎巴嫩爆发旋毛虫病。

An outbreak of trichinosis in Lebanon.

作者信息

Olaison L, Ljungström I

机构信息

Department of Infectious Diseases, University of Göteborg, Ostra Hospital, Sweden.

出版信息

Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):658-60. doi: 10.1016/0035-9203(92)90178-f.

Abstract

In 1982 an outbreak of trichinosis occurred in an area of south Lebanon consisting of 4 villages, including 6440 persons. In 267 households, involving 2456 persons, typical clinical signs of Trichinella spiralis infection could be recognized among household members. Twenty-one of these households, including 193 persons, were randomly chosen for further studies. Nearly half of the household members (46%) had clinical symptoms consistent with acute trichinosis. 12 of 16 tested persons had high anti-Trichinella antibody titres (12 positive by indirect immunofluorescence (IIF) and 11 by enzyme-linked immunosorbent assay). Class-specific antibodies, IIF-immunoglobulin (Ig) G, IgM and IgA, were detected in most tested cases. Of the remaining 4 seronegative cases, 3 had a duration of clinical symptoms < or = 12 d. High peripheral eosinophilic counts (> 20%) were noted in 8 of 16 cases. In total, 15 of 16 cases were positive by one or more of these tests. The outbreak constituted one of the most extensive single outbreaks reported with a calculated > 1000 clinical cases. The cause was attributed to consumption of raw pork meat, an ingredient of kebbeh nayyeh, a favourite Lebanese dish.

摘要

1982年,黎巴嫩南部一个包括4个村庄、共6440人的地区爆发了旋毛虫病。在267户、共2456人的家庭中,家庭成员出现了旋毛虫感染的典型临床症状。从这些家庭中随机选取了21户、共193人进行进一步研究。近一半的家庭成员(46%)有与急性旋毛虫病相符的临床症状。16名受测者中有12人抗旋毛虫抗体效价较高(间接免疫荧光法(IIF)检测12人呈阳性,酶联免疫吸附测定法检测11人呈阳性)。在大多数受测病例中检测到了类别特异性抗体,即IIF免疫球蛋白(Ig)G、IgM和IgA。其余4例血清学阴性病例中,3例临床症状持续时间≤12天。16例中有8例外周嗜酸性粒细胞计数较高(>20%)。16例中有15例通过上述一项或多项检测呈阳性。此次疫情是报告的最广泛的单次疫情之一,据计算临床病例超过1000例。病因归因于食用生猪肉,这是黎巴嫩人喜爱的菜肴“生碎肉丸子(kebbeh nayyeh)”的一种配料。

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