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使用两种检测方法对科特迪瓦的人类免疫缺陷病毒1型和2型感染进行唾液和尿液诊断。

Salivary and urinary diagnosis of human immunodeficiency viruses 1 and 2 infection in Côte d'Ivoire, using two assays.

作者信息

Gershy-Damet G M, Koffi K, Abouya L, Sasson-Morokro M, Brattegaard K, Parry J V, De Cock K M, Mortimer P P

机构信息

Institute Pasteur de Cote d'Ivoire.

出版信息

Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):670-1. doi: 10.1016/0035-9203(92)90184-e.

DOI:10.1016/0035-9203(92)90184-e
PMID:1287941
Abstract

This investigation, done at the Institut Pasteur de Cote d'Ivoire 'blind' of the previous serological findings, suggests that GACELISA, a commercial immunoglobulin G capture enzyme immunoassay for anti-human immunodeficiency virus antibody, can be successfully applied to unprocessed saliva and urine specimens. Its accuracy may be as high as that of conventional enzyme assays on serum tested under similar conditions. However, the role of GACPAT, a similar assay, as a cheap alternative screening test for urine remains in doubt unless its non-specificity can be controlled.

摘要

这项在科特迪瓦巴斯德研究所进行的调查,对之前的血清学检测结果采用“盲法”,表明GACELISA(一种用于检测抗人类免疫缺陷病毒抗体的商业免疫球蛋白G捕获酶免疫测定法)可成功应用于未经处理的唾液和尿液样本。在类似条件下检测时,其准确性可能与传统血清酶检测法一样高。然而,GACPAT(一种类似的检测法)作为一种廉价的尿液替代筛查检测法的作用仍存疑问,除非其非特异性能够得到控制。

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