Souquet Pierre-Jean
Service de pneumologie Hospices Civils de Lyon Centre hospitalier Lyon-Sud 69495 Pierre-Bénite.
Rev Prat. 2003 Apr 1;53(7):747-51.
Non small cell lung cancer is the most common histologic type (80 to 85%) with an incidence of 20 to 25,000 cases by year in France. Almost fifty per cent of cases are stage IV disease, at diagnosis and the treatment is palliative by chemotherapy. Locally advanced disease is treated by an association of chemo and radiotherapy. At the early stage, the treatment consists of surgery combined with chemotherapy. New drugs, new biologic therapeutics, the improvement of surgical procedures and radiotherapy, and combined treatment have increased the survival rate (15% at 5 years survival). Nevertheless, prevention ("war" against tobacco) early diagnosis and perhaps CT scan screening remains the best way of decreasing the number of deaths by lung cancer.
非小细胞肺癌是最常见的组织学类型(占80%至85%),在法国每年的发病率为20000至25000例。几乎50%的病例在诊断时为IV期疾病,治疗以化疗为主进行姑息治疗。局部晚期疾病采用化疗和放疗联合治疗。在早期阶段,治疗包括手术联合化疗。新药、新的生物疗法、手术程序和放疗的改进以及联合治疗提高了生存率(5年生存率为15%)。然而,预防(“与烟草作斗争”)、早期诊断以及可能的CT扫描筛查仍然是减少肺癌死亡人数的最佳方法。