Vreeland Betty, Minsky Shula, Menza Matthew, Rigassio Radler Diane, Roemheld-Hamm Beatrix, Stern Robert
Department of Psychiatry-Robert Wood Johnson Medical School and University Behavioral Health Care, University of Medicine and Dentistry of New Jersey, Piscataway, 08855, USA.
Psychiatr Serv. 2003 Aug;54(8):1155-7. doi: 10.1176/appi.ps.54.8.1155.
This study assessed the efficacy of a weight control program for patients taking atypical antipsychotics. Thirty-one patients with schizophrenia or schizoaffective disorder participated in a 12-week weight control program that incorporated nutrition, exercise, and behavioral interventions. Changes in patients' weight and in body mass index (BMI) were recorded and compared with those of 15 patients in a control group. The intervention group had a mean weight loss of 2.7 kg (six pounds) and a mean reduction of.98 BMI points, compared with a mean weight gain of 2.9 kg (6.4 pounds) and a mean gain of 1.2 BMI points in the control group. These data suggest that the intervention was effective in this group of patients. Professionals treating persons who are taking atypical antipsychotics should encourage them to engage in weight control activities.
本研究评估了针对服用非典型抗精神病药物患者的体重控制计划的效果。31名患有精神分裂症或分裂情感性障碍的患者参与了一项为期12周的体重控制计划，该计划纳入了营养、运动和行为干预措施。记录了患者体重和体重指数（BMI）的变化，并与15名对照组患者的变化进行了比较。干预组平均体重减轻了2.7千克（6磅），BMI平均降低了0.98个点，而对照组平均体重增加了2.9千克（6.4磅），BMI平均增加了1.2个点。这些数据表明该干预措施对这组患者有效。治疗服用非典型抗精神病药物患者的专业人员应鼓励他们参与体重控制活动。
