Steinberg William M
Pancreas. 2003 Aug;27(2):118-21. doi: 10.1097/00006676-200308000-00002.
The risk benefit ratio of measuring the sphincter of Oddi pressure and performing sphincterotomy in patients with idiopathic acute pancreatitis with high sphincter pressures has not been assessed. Few healthy controls have had sphincter measurements so that the definition of an abnormal sphincter remains understudied. The procedures involved have significant risks and the benefits are hard to measure considering the variable natural history of this disorder. No prospective, randomized investigations have been performed to evaluate efficacy of these invasive procedures. It is the author's opinion that until appropriate studies prove efficacy that these interventions be considered experimental.
对于特发性急性胰腺炎且括约肌压力较高的患者，测量Oddi括约肌压力并进行括约肌切开术的风险效益比尚未得到评估。很少有健康对照者进行过括约肌测量，因此异常括约肌的定义仍未得到充分研究。所涉及的操作有重大风险，考虑到这种疾病自然病程的多变性，其益处难以衡量。尚未进行前瞻性、随机研究来评估这些侵入性操作的疗效。作者认为，在适当的研究证明其疗效之前，这些干预措施应被视为试验性的。
