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谷氨酰胺与急性疾病

Glutamine and acute illness.

作者信息

Wernerman Jan

机构信息

Department of Anesthesiology and Intensive Care, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden.

出版信息

Curr Opin Crit Care. 2003 Aug;9(4):279-85. doi: 10.1097/00075198-200308000-00005.

DOI:10.1097/00075198-200308000-00005
PMID:12883282
Abstract

This is a literature review over a time period of the past 2 years concerning glutamine in clinical nutrition. Emphasis is put upon studies of glutamine in clinical settings, but a brief overview of the large range of literature over the role of glutamine in various experimental settings is also included. The most interesting concept for the past 2 years is the suggestion to use plasma glutamine concentration at admission to the intensive care unit as a prognostic marker and as a possible indicator for indication of glutamine supplementation.

摘要

这是一篇关于过去两年临床营养中谷氨酰胺的文献综述。重点在于谷氨酰胺在临床环境中的研究,但也包括了对谷氨酰胺在各种实验环境中作用的大量文献的简要概述。过去两年最有趣的概念是建议将重症监护病房入院时的血浆谷氨酰胺浓度用作预后标志物,并作为谷氨酰胺补充指征的可能指标。

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1
Glutamine and acute illness.谷氨酰胺与急性疾病
Curr Opin Crit Care. 2003 Aug;9(4):279-85. doi: 10.1097/00075198-200308000-00005.
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引用本文的文献

1
Enteral nutrition in critical care.重症监护中的肠内营养
J Clin Med Res. 2013 Feb;5(1):1-11. doi: 10.4021/jocmr1210w. Epub 2013 Jan 11.
2
Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial.静脉补充谷氨酰胺对接受肠内营养的创伤患者的影响研究方案(GLINT研究):一项前瞻性、盲法、随机、安慰剂对照临床试验。
BMJ Open. 2011 Nov 14;1(2):e000334. doi: 10.1136/bmjopen-2011-000334. Print 2011.
3
"Metabolic staging" after major trauma - a guide for clinical decision making?
严重创伤后的“代谢分期”——临床决策指南?
Scand J Trauma Resusc Emerg Med. 2010 Jun 17;18:34. doi: 10.1186/1757-7241-18-34.
4
Metabolic changes after polytrauma: an imperative for early nutritional support.多发伤后的代谢变化:早期营养支持的必要性
World J Emerg Surg. 2006 Oct 4;1:29. doi: 10.1186/1749-7922-1-29.