[利尿剂布非诺克斯的免疫调节特性]
[The immunomodulating properties of the diuretic bufenoks].
作者信息
Romanova T V, Prokina V V, Kolesnikova O P, Kudaeva O T, Kozlov V A
出版信息
Biull Eksp Biol Med. 1992 Oct;114(10):387-9.
PMID:1288697
Abstract
Bufenox, a diuretic with a sodium-uretic and light potassium--uretic effect, has an immediate but short-term effect, stimulates IgM antibody production, depressed delayed-type hypersensitivity. The immunomodulating effect of bufenox may be due to changes in Na+ ions concentrations since sodium load abrogates immunoactive properties of the drug.
摘要
布非诺克斯是一种具有排钠利尿和轻度排钾利尿作用的利尿剂，起效迅速但作用短暂，能刺激IgM抗体产生，抑制迟发型超敏反应。布非诺克斯的免疫调节作用可能归因于钠离子浓度的变化，因为钠负荷会消除该药物的免疫活性特性。
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