Hamano Satoshi, Kiyoshima Keijiro, Nakatsu Hiroomi, Murakami Shino, Igarashi Tatsuo, Ito Haruo
Department of Urology, Asahi General Hospital, Asahi, Japan.
Urol Int. 2003;71(2):178-83. doi: 10.1159/000071843.
To report on the clinical features, diagnosis, and treatment of psoas abscess (PA) with special attention to the presence of septic shock.
This study included 17 patients (mean age 66.2, range 43-81 years) with PA. Treatment consisted of intravenous administration of antibiotics and abscess drainage, either surgical or percutaneous with ultrasound guidance.
The typical patients presented with fever >38 degrees C (16/17, 94%), pain in back, flank, or abdomen (15/17, 88%), hip flexion contracture with pain extension (14/17, 82%), and mass felt in the flank (5/17, 29%). All 8 patients without septic shock (100%) had the clinical triad (fever, pain in back, flank, or abdomen, and hip flexion contracture) as compared with 4 of 9 patients with septic shock (44%) (p = 0.012). The duration of symptoms before hospitalization was significantly shorter in the patients with septic shock (median 2, range 1-5 days) than in those without septic shock (median 18.5, range 11-63 days; (p = 0.0005). The mortality rates were 33% (3 of 9) and 0% (0 of 8) in the patients with and without septic shock, respectively (p = 0.071).
PA patients with septic shock had a tendency to have nonspecific symptoms and an occult clinical course as compared with those without septic shock. A delay in diagnosis and treatment can result in a worse clinical outcome (death or totally disabled state). Increased awareness of this condition should lead to earlier diagnosis and treatment with improved outcomes.
报告腰大肌脓肿(PA)的临床特征、诊断及治疗情况,特别关注脓毒性休克的存在。
本研究纳入了17例PA患者(平均年龄66.2岁,范围43 - 81岁)。治疗包括静脉使用抗生素以及脓肿引流,引流方式为手术引流或在超声引导下经皮引流。
典型患者表现为体温>38摄氏度(16/17,94%)、背部、侧腹或腹部疼痛(15/17,88%)、髋关节屈曲挛缩伴疼痛性伸展(14/17,82%)以及侧腹可触及肿块(5/17,29%)。所有8例无脓毒性休克的患者(100%)具有临床三联征(发热、背部、侧腹或腹部疼痛以及髋关节屈曲挛缩),而9例有脓毒性休克的患者中只有4例(44%)有此三联征(p = 0.012)。有脓毒性休克的患者住院前症状持续时间显著短于无脓毒性休克的患者(中位数2天,范围1 - 5天),无脓毒性休克的患者症状持续时间中位数为18.5天,范围11 - 63天(p = 0.0005)。有脓毒性休克和无脓毒性休克患者的死亡率分别为33%(9例中的3例)和0%(8例中的0例)(p = 0.071)。
与无脓毒性休克的PA患者相比,有脓毒性休克的患者往往具有非特异性症状和隐匿的临床病程。诊断和治疗延迟可导致更差的临床结局(死亡或完全残疾状态)。提高对这种疾病的认识应能实现更早的诊断和治疗,从而改善结局。