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肾囊肿:经皮乙醇注射能否被视为手术的替代方法?

Renal cysts: can percutaneous ethanol injections be considered an alternative to surgery?

作者信息

Gasparini Daniele, Sponza Massimo, Valotto Claudio, Marzio Andrea, Luciani Lorenzo G, Zattoni Filiberto

机构信息

Department of Radiology, S.M. Misericordia Hospital, Udine, Italy.

出版信息

Urol Int. 2003;71(2):197-200. doi: 10.1159/000071846.

Abstract

AIM

To evaluate the efficacy of a new sclerotization technique with pure ethanol in the treatment of symptomatic renal cysts.

PATIENTS AND METHODS

Fourteen patients having renal cysts with a meant diameter of 10 (range 5-15) cm were treated. Our technique includes: ultrasound-guided percutaneous puncture with an 18-gauge needle, positioning of a 5-Fr catheter, complete cyst fluid aspiration, injection of pure alcohol equal to 15% of the initial cyst volume, and alcohol aspiration after 90 min. The procedure was repeated eight times within 5 days. The patients were followed up by ultrasound and/or CT scan for 1 year.

RESULTS

All patients became symptom free. Follow-up showed a progressive reduction of the cyst diameter in all cases. Three cysts only (in 2 patients; cyst diameter <2 cm) persisted after 12 months. No significant complications were observed.

CONCLUSIONS

In our experience, injections of pure ethanol in renal cysts, repeated after some days, were effective in eliminating recurrences and related symptoms. The procedure was not associated with significant complications. Our findings suggest that it be considered the first-choice procedure in the treatment of renal cysts, due to the good results and the low cost of ethanol.

摘要

目的

评估一种使用纯乙醇的新型硬化技术治疗有症状肾囊肿的疗效。

患者与方法

对14例平均直径为10(范围5 - 15)cm的肾囊肿患者进行治疗。我们的技术包括:用18号针在超声引导下经皮穿刺,放置一根5F导管,完全抽吸囊肿液,注入相当于初始囊肿体积15%的纯酒精,90分钟后抽吸酒精。该操作在5天内重复8次。通过超声和/或CT扫描对患者进行1年的随访。

结果

所有患者症状消失。随访显示所有病例囊肿直径均逐渐减小。12个月后仅3个囊肿(2例患者;囊肿直径<2 cm)持续存在。未观察到明显并发症。

结论

根据我们的经验,数日后重复向肾囊肿内注射纯乙醇可有效消除复发及相关症状。该操作未伴有明显并发症。我们的研究结果表明,鉴于效果良好且乙醇成本低,应将其视为肾囊肿治疗的首选方法。

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