Eckhardt P G, Heymans H S, Kneepkens C M
Tijdschr Kindergeneeskd. 1986 Feb;54(1):12-5.
Transient hyperphosphatasemia of infancy. Striking transient increases in serum alkaline phosphatase in nine new cases are reported. The etiology is still unknown. The patients were 6.5 months to 30 months of age and none showed any clinical evidence of hepatic or skeletal disease. Values became normal within 12 weeks in all patients. It is important to know this condition to avoid unnecessary and expensive diagnostic procedures. Though hyperphosphatasemia does not seem to give any problems we recommend a brief diagnostic protocol in order to recognize transient hyperphosphatasemia of infancy.
婴儿期短暂性高磷酸酶血症。报告了9例新病例中血清碱性磷酸酶显著短暂升高的情况。病因仍不明。患者年龄在6.5个月至30个月之间,均未表现出任何肝脏或骨骼疾病的临床证据。所有患者的数值在12周内恢复正常。了解这种情况以避免不必要且昂贵的诊断程序很重要。尽管高磷酸酶血症似乎不会引发任何问题,但我们建议采用简短的诊断方案以识别婴儿期短暂性高磷酸酶血症。