Søndergaard C, Olsen J, Friis-Haschè E, Dirdal M, Thrane N, Sørensen H Toft
The Danish Epidemiology Science Centre, University of Aarhus, Denmark.
Acta Paediatr. 2003 Jul;92(7):811-6. doi: 10.1080/08035250310003857.
To examine the association between psychosocial exposures during pregnancy and the risk of infantile colic.
The study included 378 infants and was conducted as a substudy of the Danish National Birth Cohort from 1997 to 1999, with prenatal data collected twice during pregnancy. A diary with a record for postpartum weeks 4-8 was used to quantify the amount of the infants' crying and fussing.
The cumulative incidence proportion of infantile colic was 8.2%. A threefold increased risk of infantile colic (OR = 3.7; 95% CI: 1.1-13.2) was found for mothers who reported distress during pregnancy. Close to a twofold increased risk of IC was found for the women who scored higher than 8 on the psychological distress scale (adjusted OR = 1.9; 95% CI: 0.5-7.2).
The results indicate that general distress during pregnancy influences the risk of infantile colic. Whether or not this relationship is causal requires further investigations.
研究孕期心理社会暴露与婴儿腹绞痛风险之间的关联。
该研究纳入了378名婴儿，作为1997年至1999年丹麦国家出生队列的一项子研究，在孕期收集了两次产前数据。使用一本记录产后第4至8周情况的日记来量化婴儿哭闹和烦躁的程度。
婴儿腹绞痛的累积发病率为8.2%。报告孕期有困扰的母亲患婴儿腹绞痛的风险增加了两倍（比值比=3.7；95%置信区间：1.1-13.2）。心理困扰量表得分高于8分的女性患婴儿腹绞痛的风险增加了近两倍（调整后比值比=1.9；95%置信区间：0.5-7.2）。
结果表明孕期的一般困扰会影响婴儿腹绞痛的风险。这种关系是否具有因果性需要进一步研究。
