Kumar D, Grimer R J, Abudu A, Carter S R, Tillman R M
Oncology Service, Royal Orthopaedic Hospital, Bristol Road South, Northfield, England, Birmingham B31 2AP, UK.
J Bone Joint Surg Br. 2003 Jul;85(5):717-22.
We studied 100 patients who had undergone endoprosthetic replacement of the proximal humerus between 1976 and 1998. The outcome was assessed with regard to the survivorship of the patients, the salvaged limbs and the prostheses. Function was determined in the 47 surviving patients, of whom 30 were assessed using the Musculo-Skeletal Tumour Society (MSTS) rating scale and 38 completed the Toronto Extremity Salvage Score (TESS) questionnaire. The median age of the patients was 34 years (10 to 80). The mean follow-up period for surviving patients was nine years (2 to 20). The mean MSTS score at follow-up was 79% and the mean TESS score was 72%. The length of bone which was resected influenced the functional outcome. Abduction of the shoulder was to 45 degrees in most patients. The overall survival was 42% at ten years and that of the limb without amputation 93%. The survival of the prostheses using mechanical failure as the endpoint was 86.5% at 20 years. Endoprosthetic replacement of the proximal humerus is a predictable procedure providing reasonable function of the arm with a low rate of complications at long-term follow-up.
我们研究了1976年至1998年间接受肱骨近端假体置换术的100例患者。评估了患者、保留肢体和假体的生存率。对47例存活患者的功能进行了测定,其中30例使用肌肉骨骼肿瘤学会(MSTS)评分量表进行评估,38例完成了多伦多肢体挽救评分(TESS)问卷。患者的中位年龄为34岁(10至80岁)。存活患者的平均随访期为9年(2至20年)。随访时MSTS评分的平均值为79%,TESS评分的平均值为72%。切除的骨长度影响功能结果。大多数患者的肩关节外展至45度。10年时的总生存率为42%,未截肢肢体的生存率为93%。以机械故障为终点的假体20年生存率为86.5%。肱骨近端假体置换术是一种可预测的手术,能使手臂功能合理,长期随访并发症发生率低。