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在以色列六日战争或赎罪日战争期间，精神分裂症风险与产前应激暴露之间没有关联。

No relationship between risk of schizophrenia and prenatal exposure to stress during the Six-Day War or Yom Kippur War in Israel.

作者信息

Selten Jean-Paul, Cantor-Graae Elizabeth, Nahon Daniella, Levav Itzhak, Aleman André, Kahn René S

机构信息

Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center, P.O. Box 85500, 3508 GA Utrecht, Ref. Nr A00.241, The Netherlands.

出版信息

Schizophr Res. 2003 Sep 1;63(1-2):131-5. doi: 10.1016/s0920-9964(02)00375-4.

DOI:10.1016/s0920-9964(02)00375-4
PMID:12892867
Abstract

AIM

Maternal stress during pregnancy is a possible risk factor for schizophrenia in the offspring. Using data from the Israel Psychiatric Registry we examined the impact of wars in Israel.

METHOD

Retrospective birth cohort study.

RESULTS

Relative risks for cohorts exposed to Six-Day War and Yom Kippur War were 0.98 (95% CI: 0.85-1.13) and 1.00 (0.86-1.16).

CONCLUSION

The evidence for maternal stress as a risk factor for schizophrenia remains insufficient.

摘要

目的

孕期母亲压力是后代患精神分裂症的一个潜在风险因素。我们利用以色列精神病学登记处的数据研究了以色列战争的影响。

方法

回顾性出生队列研究。

结果

经历六日战争和赎罪日战争队列的相对风险分别为0.98（95%可信区间：0.85 - 1.13）和1.00（0.86 - 1.16）。

结论

母亲压力作为精神分裂症风险因素的证据仍然不足。

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