Forster M C, Straw R
Derbyshire Royal Infirmary, London Road, Derby, UK.
Knee. 2003 Sep;10(3):291-3. doi: 10.1016/s0968-0160(02)00145-x.
Thirty-eight patients with symptomatic knee osteoarthritis without mechanical symptoms were randomised after informed consent to receive either a course of intra-articular Hyalgan injections or an arthroscopic washout. The patients were prospectively assessed pre-intervention, 6 weeks, 3 months, 6 months and 1 year using a 10 cm visual analogue pain score, the Knee Society function score and the Lequesne index. There was no significant difference between the two groups at 6 weeks, 3 months, 6 months or 1 year. The use of intra-articular Hyalgan injections in patients with knee osteoarthritis without mechanical symptoms gives results comparable with arthroscopic washout. Hyalgan is an alternative to arthroscopy in this patient group. Further study is needed to confirm these findings and improve patient selection.
38例无机械症状的有症状膝关节骨关节炎患者在获得知情同意后，被随机分配接受关节内注射透明质酸钠疗程或关节镜冲洗。在干预前、6周、3个月、6个月和1年时，使用10厘米视觉模拟疼痛评分、膝关节协会功能评分和Lequesne指数对患者进行前瞻性评估。在6周、3个月、6个月或1年时，两组之间没有显著差异。对于无机械症状的膝关节骨关节炎患者，关节内注射透明质酸钠的效果与关节镜冲洗相当。在该患者群体中，透明质酸钠是关节镜检查的替代方法。需要进一步研究以证实这些发现并改进患者选择。
