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高剂量率近距离放射治疗源定位:使用金刚石探测器的位置分辨率

High dose-rate brachytherapy source localization: positional resolution using a diamond detector.

作者信息

Nakano T, Suchowerska N, Bilek M M, McKenzie D R, Ng N, Kron T

机构信息

Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, NSW 2052, Australia.

出版信息

Phys Med Biol. 2003 Jul 21;48(14):2133-46. doi: 10.1088/0031-9155/48/14/307.

Abstract

A potential real-time source position verification process for high dose-rate (HDR) brachytherapy treatment is described. This process is intended to provide immediate confirmation that a treatment is proceeding according to plan, so that corrective action can be taken if necessary. We show that three dosimeters are in principle sufficient and demonstrate the feasibility of the process using a diamond detector and an Ir-192 source. An error analysis including all identified sources of error shows that this detector is capable of locating the distance to the source to within 2 mm for distances up to 12 cm. This positional accuracy is less than the diameter of typical HDR catheters indicating that a diamond detector can be used to accurately determine the distance to the source. The uncertainty in the distance is found to increase with distance.

摘要

描述了一种用于高剂量率(HDR)近距离放射治疗的潜在实时源位置验证过程。该过程旨在立即确认治疗是否按计划进行,以便在必要时采取纠正措施。我们表明,原则上三个剂量计就足够了,并使用金刚石探测器和铱-192源证明了该过程的可行性。包括所有已识别误差源的误差分析表明,对于距离源高达12厘米的情况,该探测器能够将到源的距离定位在2毫米以内。这种位置精度小于典型HDR导管的直径,这表明金刚石探测器可用于精确确定到源的距离。发现距离的不确定性会随着距离增加。

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