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来自非洲吊灯树果实的环烯醚萜类化合物。

Iridoids from Kigelia pinnata DC. fruits.

作者信息

Gouda Yaser G, Abdel-baky Afaf M, Darwish Faten M, Mohamed Khaled M, Kasai Ryoji, Yamasaki Kazuo

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, 71526 Assiut, Egypt.

出版信息

Phytochemistry. 2003 Aug;63(8):887-92. doi: 10.1016/s0031-9422(03)00262-0.

DOI:10.1016/s0031-9422(03)00262-0
PMID:12895535
Abstract

From the fruits of Kigelia pinnata DC., a new furanone derivative formulated as 3-(2'-hydroxyethyl)-5-(2"-hydroxypropyl)-dihydrofuran-2(3H)-one (1), and four new iridoids named; 7-hydroxy viteoid II (2), 7-hydroxy eucommic acid (3), 7-hydroxy-10-deoxyeucommiol (4) and 10-deoxyeucommiol (5) have been isolated together with seven known iridoids, jiofuran (6), jioglutolide (7), 1-dehydroxy-3,4-dihydroaucubigenin (8), des-p-hydroxybenzoyl kisasagenol B (9), ajugol (10), verminoside (11) and 6-trans-caffeoyl ajugol (12). The structures of the isolated compounds were characterized by different spectroscopic methods.

摘要

从吊灯树果实中,分离得到一种新的呋喃酮衍生物,其结构为3-(2'-羟乙基)-5-(2"-羟丙基)-二氢呋喃-2(3H)-酮(1),以及四种新的环烯醚萜类化合物,分别为7-羟基viteoid II(2)、7-羟基杜仲酸(3)、7-羟基-10-脱氧杜仲醇(4)和10-脱氧杜仲醇(5),同时还分离出七种已知的环烯醚萜类化合物,分别为焦呋喃(6)、焦谷醇内酯(7)、1-脱羟基-3,4-二氢桃叶珊瑚苷元(8)、去对羟基苯甲酰基奇萨皂苷元B(9)、筋骨草醇(10)、马鞭草苷(11)和6-反式咖啡酰筋骨草醇(12)。通过不同的光谱方法对分离得到的化合物结构进行了表征。

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