Rozhkov G I, Chalenko V G, Popova I A, Trushnikova A G, Volodina I K
Zh Mikrobiol Epidemiol Immunobiol. 1975 May(5):83-8.
The authors demonstrated a marked dissociation of the Neisseria meningitis cultures and the capacity to their rapid change from S- to R-forms. Differential signs of the S- and R-forms are described. Differences in the degree of dissociation of the cultures depending on their origin were shown: strains isolated from the cerebrospinal fluid and the blood of patients with meningitis proved to be less dissociated, and those isolated from carriers--more dissociated. Transfers from media to media and adaptation of cultures to artificial nutrient media produced the greatest influence on dissociation of the freshly isolated strains.
作者证明了脑膜炎奈瑟菌培养物与其从S型快速转变为R型的能力之间存在明显的解离现象。描述了S型和R型的鉴别特征。结果表明，培养物的解离程度因其来源不同而存在差异：从脑膜炎患者的脑脊液和血液中分离出的菌株解离程度较低，而从携带者中分离出的菌株解离程度较高。培养基之间的转接以及培养物对人工营养培养基的适应对新分离菌株的解离产生了最大影响。
