Brookes M J, Manjunatha S, Allen C A, Cox M
Department of Gastroenterology, City General Hospital, Stoke-on-Trent.
Postgrad Med J. 2003 Jul;79(933):416-7. doi: 10.1136/pmj.79.933.416.
Brunner's gland hamartomas are rare tumours of the duodenum. These lesions have previously been described as being benign, with no malignant potential. A case report is presented of a Brunner's gland hamartoma, whose histology revealed a focus of well marked epithelial dysplasia. This case suggests a dysplastic stage in the natural history of Brunner's gland hamartoma, and questions the malignant potential of these lesions.
布伦纳腺错构瘤是十二指肠的罕见肿瘤。这些病变以前被描述为良性，无恶变潜能。本文报告一例布伦纳腺错构瘤，其组织学显示有一个明显的上皮发育异常灶。该病例提示布伦纳腺错构瘤自然病程中存在发育异常阶段，并对这些病变的恶变潜能提出质疑。
