含氧磷酸的烷基化反应。
Alkylation reaction of phosphorus oxyacids.
作者信息
Ayukawa H, Ohuchi S, Higashiya S, Singh R K, Ishikawa M, Hata T
机构信息
Department of Life Chemistry, Tokyo Institute of Technology, Yokohama, Japan.
出版信息
Nucleic Acids Symp Ser. 1992(27):91-2.
PMID:1289839
Abstract
Alkylation reactions of phosphorus oxyacids (i.e. phosphoric acid, phosphorous acid, hypophosphorous acid) were examined by means of several methods for the synthesis of the corresponding esters. These reactions were applied to the synthesis of oligonucleotide having phosphotriester bond or phosphonate diester bond.
摘要
通过几种合成相应酯的方法研究了含氧磷酸（即磷酸、亚磷酸、次磷酸）的烷基化反应。这些反应被应用于合成具有磷酸三酯键或膦酸二酯键的寡核苷酸。
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