Nattermann C, Goldschmidt A J, Dancygier H
Medizinische Klinik II, Städtischen Kliniken Offenbach, J.W. Goethe-Universität, Frankfurt/Main.
Ultraschall Med. 1992 Dec;13(6):263-70. doi: 10.1055/s-2007-1005320.
EUS and ERP were performed in 114 patients. 94 patients (32 women, 62 men; mean age 53 years; range 29-78 years) had inflammatory pancreatic disease while 20 patients (6 women, 14 men; mean age 54 years; range 28-78 years) without disease of the pancreas served as controls. ERP-findings served as the gold standard and were classified into stages I-III according to the Cambridge classification. On ERP 51 patients had duct changes typical of chronic pancreatitis (CP). Control cases always displayed a homogeneous echo pattern and a regular outer margin of the pancreas. Abnormal EUS findings were present in all patients with ERP-stages II and III and in 88% of patients with ERP-stage I. 63% of patients with a normal pancreatogram, i.e. ERP-stage 0 showed pathological alterations on EUS examination. Diffuse alterations of the echopattern were seen in 75% of CP patients with stage I, in 88% with stage II and in 96% with stage III. Alternating echo-poor/echo-dense areas were present in 50% of stage I, in 88% of stage II, and in 81% of stage III cases, respectively. 38% of stage I, 56% of stage II, and 27% of stage III cases displayed a lobulated appearance of pancreatic parenchyma. In 80% of the patients these findings were combined with an irregularly lined pancreatic surface. This same combination of EUS-findings in proven CP was also present in 30% of patients with completely normal pancreatic ducts, i.e. ERP-stage 0. Changes of the main pancreatic duct in stages II and III were also seen with EUS in 81% and 96%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
114例患者接受了超声内镜（EUS）和内镜逆行胰胆管造影（ERP）检查。94例患者（32例女性，62例男性；平均年龄53岁；范围29 - 78岁）患有炎性胰腺疾病，而20例无胰腺疾病的患者（6例女性，14例男性；平均年龄54岁；范围28 - 78岁）作为对照。ERP检查结果作为金标准，并根据剑桥分类法分为I - III期。在ERP检查中，51例患者有典型的慢性胰腺炎（CP）导管改变。对照病例胰腺总是呈现均匀的回声模式和规则的外缘。所有ERP II期和III期患者以及88%的ERP I期患者存在异常EUS表现。63%胰管造影正常（即ERP 0期）的患者在EUS检查中显示病理改变。I期CP患者中75%、II期88%、III期96%可见回声模式的弥漫性改变。I期50%、II期88%、III期81%分别存在低回声/高回声交替区域。I期38%、II期56%、III期27%的病例胰腺实质呈分叶状外观。80%的患者这些表现伴有胰腺表面边界不规则。在30%胰管完全正常（即ERP 0期）的患者中也存在已证实的CP中相同的EUS表现组合。II期和III期主胰管的改变在EUS检查中分别也有81%和96%可见。（摘要截断于250字）
