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哺乳动物大脑的感觉室周器官。

The sensory circumventricular organs of the mammalian brain.

作者信息

McKinley M J, McAllen R M, Davern P, Giles M E, Penschow J, Sunn N, Uschakov A, Oldfield B J

机构信息

Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Victoria, 3010, Australia.

出版信息

Adv Anat Embryol Cell Biol. 2003;172:III-XII, 1-122, back cover. doi: 10.1007/978-3-642-55532-9.

Abstract

The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the brain in which neurons are exposed to the chemical environment of the systemic circulation. Therefore they are ideally placed to monitor the changes in osmotic, ionic and hormonal composition of the blood. This book describes their. General structure and relationship to the cerebral ventricles Regional subdivisions Vasculature and barrier properties Neurons, glia and ependymal cells Receptors, neurotransmitters, neuropeptides and enzymes Neuroanatomical connections Functions.

摘要

大脑的三个感觉室周器官,即穹窿下器官、终板血管器和最后区,缺乏血脑屏障,是大脑中神经元暴露于体循环化学环境的唯一区域。因此,它们处于理想位置,能够监测血液中渗透压、离子和激素成分的变化。本书描述了它们的:一般结构及其与脑室的关系、区域细分、脉管系统和屏障特性、神经元、神经胶质细胞和室管膜细胞、受体、神经递质、神经肽和酶、神经解剖连接以及功能。

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