Miyoshi M, Sakurai T, Kodama S
Department of Pediatrics, Himeji Red Cross Hospital.
Arerugi. 1992 Dec;41(12):1672-8.
Serum ECP levels, serum MBP levels and blood eosinophil counts (Eo) were studied in patients prepared for asthma attack. Five severely asthmatic children were studied. Samples were taken just before their 33 times of home stay loading test. Serum ECP levels were significantly higher in the patients who suffered asthma attacks during their home-stay period than in those who did not. In addition, serum ECP levels were higher in the patients whose asthma attack started less than 12 hours after they returned home. However, there was no significant correlation either in serum MBP levels or peripheral eosinophil counts between these groups. These findings suggested that serum ECP levels increased in patients prepared for asthma attack.
对准备发作哮喘的患者进行了血清嗜酸性粒细胞阳离子蛋白（ECP）水平、血清髓鞘碱性蛋白（MBP）水平和血液嗜酸性粒细胞计数（Eo）的研究。对5名重度哮喘儿童进行了研究。在他们第33次居家激发试验前采集样本。在家居期间发作哮喘的患者血清ECP水平显著高于未发作哮喘的患者。此外，哮喘发作在回家后不到12小时开始的患者血清ECP水平更高。然而，这些组之间血清MBP水平或外周嗜酸性粒细胞计数均无显著相关性。这些发现提示，准备发作哮喘的患者血清ECP水平升高。
