Beets-Tan R G H, Beets G L
Department of Radiology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands.
Int J Colorectal Dis. 2003 Sep;18(5):385-91. doi: 10.1007/s00384-003-0480-5. Epub 2003 Mar 7.
One of the concerns after rectal cancer surgery is the local recurrence rate. Randomized trials have shown that the best local control rate for rectal cancer patients overall is obtained by a short preoperative course of radiotherapy followed by a total mesorectal excision, but there are however subgroups of rectal cancer patients with varying risks of recurrences.
At one end of the continuum are patients with stage I disease who are at very low risk of local recurrence. At the other end are the patients with locally advanced tumor who are at very high risk, and who would benefit from a more extensive neoadjuvant treatment schedule. This kind of differentiated treatment can be performed only when there is an accurate tool to identify preoperatively the different risk groups. There is recent evidence, suggesting that MRI can serve for this purpose, because it accurately predicts the tumor free circumferential resection margin at TME.
This article provides a literature review of the value of preoperative imaging in rectal cancer surgery.
直肠癌手术后令人担忧的问题之一是局部复发率。随机试验表明,总体而言,直肠癌患者通过术前短疗程放疗后行全直肠系膜切除术可获得最佳的局部控制率,但然而,直肠癌患者存在不同的复发风险亚组。
在这个连续统一体的一端是I期疾病患者,其局部复发风险非常低。另一端是局部晚期肿瘤患者,其风险非常高,他们将从更广泛的新辅助治疗方案中获益。只有当有准确的工具能够术前识别不同风险组时,才能进行这种差异化治疗。最近有证据表明,MRI可用于此目的,因为它能准确预测全直肠系膜切除术中肿瘤的环周切缘。
本文对术前影像学在直肠癌手术中的价值进行了文献综述。