Gooris Peter J J, Vermey Bert, de Visscher Jan G A M, Roodenburg Jan L N
Department of Oral and Maxillogacial Surgery, Amphia Hospita Brenda, The Netherland.
J Oral Maxillofac Surg. 2003 Aug;61(8):890-4; discussion 895-7. doi: 10.1016/s0278-2391(03)00245-3.
Our goal was to evaluate the role of frozen section margin examination in the surgical management of squamous cell carcinoma of the lower lip.
We reviewed frozen section examination of the resection surfaces of 131 consecutive patients surgically treated for squamous cell carcinoma of the lower lip during the period January 1980 to January 1999. When invasive carcinoma or carcinoma in situ was present at the resection surface, the margin was defined as positive and re-resection was performed.
A peroperative positive margin was seen in 18 of 131 (14%). In 8 patients (6%), a local recurrence developed.
Frozen section examination for margin assessment in the surgical treatment of lip cancer is a reliable technique to control the radicality of the procedure; a secondary surgical procedure or postoperative radiotherapy can be reduced. However, a tumor-free resection surface does not guarantee that local recurrence will not occur.
我们的目标是评估冰冻切片边缘检查在下唇鳞状细胞癌手术治疗中的作用。
我们回顾了1980年1月至1999年1月期间连续131例接受手术治疗的下唇鳞状细胞癌患者切除表面的冰冻切片检查。当切除表面存在浸润性癌或原位癌时,边缘被定义为阳性,并进行再次切除。
131例中有18例(14%)术中边缘阳性。8例(6%)出现局部复发。
在唇癌手术治疗中,冰冻切片检查用于边缘评估是一种控制手术根治性的可靠技术;可以减少二次手术或术后放疗。然而,切除表面无肿瘤并不能保证不会发生局部复发。