Sansone Randy A, Sansone Lori A
Wright State University, Dayton, Ohio, USA.
Int J Psychiatry Med. 2003;33(1):103-5. doi: 10.2190/L2M6-Y6XT-KR7U-CAVT.
Empirical studies with humans suggest that selective serotonin reuptake inhibitors (SSRIs) may, through increases in serotonergic activity, increase insulin secretion, increase insulin sensitivity, and lower serum glucose levels. Indeed, the potentially beneficial effects of SSRI treatment in diabetics are documented. However, we describe the case of a female, with diet-controlled, type 2 diabetes, whose glucose levels increased with exposure to sertraline.
针对人类的实证研究表明，选择性5-羟色胺再摄取抑制剂（SSRI）可能通过增强血清素活性，增加胰岛素分泌、提高胰岛素敏感性并降低血糖水平。事实上，SSRI治疗对糖尿病患者的潜在益处已有文献记载。然而，我们在此描述一位通过饮食控制2型糖尿病的女性病例，其血糖水平在服用舍曲林后升高。
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