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亚临床甲状腺疾病:特洛伊木马的威胁。

Subclinical thyroid disorders: the menace of the Trojan horse.

作者信息

Duntas L H

机构信息

Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, Athens, Greece.

出版信息

J Endocrinol Invest. 2003 May;26(5):472-80. doi: 10.1007/BF03345205.

Abstract

This review aims at summarizing some new data regarding the so-called subclinical thyroid disease and incorporate the knowledge in order to provide a basis for a more careful approach to these morbidities. SHyper represents a considerable risk factor for atrial fibrillation in the elderly and also for osteoporosis, which is a major cause of morbidity in postmenopausal women. SHypo is not an innocuous condition. It progresses to thyroid failure in patients with positive thyroid antibodies, it affects neurobehavior, it may influence cardiac contractility at exercise and it is associated with an impaired lipid profile that may provoke atherosclerosis. Therefore, both conditions should be screened more carefully in the community and treatment should be more often considered.

摘要

本综述旨在总结有关所谓亚临床甲状腺疾病的一些新数据,并整合相关知识,以便为更谨慎地处理这些疾病提供依据。亚临床甲状腺功能亢进是老年人房颤的一个相当大的危险因素,也是绝经后女性发病的主要原因骨质疏松症的危险因素。亚临床甲状腺功能减退并非无害状态。在甲状腺抗体呈阳性的患者中,它会发展为甲状腺功能衰竭,会影响神经行为,可能会在运动时影响心脏收缩力,并且与可能引发动脉粥样硬化的脂质异常有关。因此,社区应更仔细地筛查这两种情况,并且应更经常考虑进行治疗。

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