Scavarda D, Bednarek N, Litre F, Koch C, Lena G, Morville P, Rousseaux P
Department of Pediatric Neurosurgery, Hôpital des Enfants, La Timone, 13385 Marseille Cedex 05, France.
Childs Nerv Syst. 2003 Nov;19(10-11):756-9. doi: 10.1007/s00381-003-0805-2. Epub 2003 Aug 8.
The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain the mechanisms of this stenosis.
From January 1996 to June 2002, 1,046 premature infants were admitted to our institution. Thirty-six neonates suffered from grade 3 or 4 intraventricular hemorrhage (Papile grading), of whom 16 died. Twenty patients survived and a ventriculoperitoneal shunt was inserted in 7 infants. Four patients underwent a neuroendoscopic third ventriculostomy. Follow-up was carried out, twice a month during the first 2 months and subsequently twice a year.
In 2 children NTV was an effective treatment for hydrocephalus with an average follow-up of 29 months. The specific pattern concerning these patients is the long delay before obstructive hydrocephalus and the visualization of de novo obstruction with MRI. The biological explanation must be investigated.
本研究的目的是证明患有脑室内出血（IVH）的早产儿中导水管狭窄的延迟发生，并试图解释这种狭窄的机制。
1996年1月至2002年6月，1046名早产儿入住我院。36名新生儿患有3级或4级脑室内出血（Papile分级），其中16名死亡。20名患者存活，7名婴儿接受了脑室腹腔分流术。4名患者接受了神经内镜下第三脑室造瘘术。进行随访，最初2个月每月随访2次，随后每年随访2次。
在2名儿童中，神经内镜下第三脑室造瘘术是治疗脑积水的有效方法，平均随访29个月。这些患者的特定模式是梗阻性脑积水出现前的长时间延迟以及MRI显示的新发梗阻。必须研究其生物学解释。
