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沙特绝经后女性骨质疏松症的双能X线骨密度检测

Osteoporosis in postmenopausal Saudi women using dual x-ray bone densitometry.

作者信息

El-Desouki Mahmoud I

机构信息

Department of Nuclear Medicine, College of Medicine, King Khalid University Hospital, PO Box 780546, Riyadh 11472, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2003 Sep;24(9):953-6.

Abstract

OBJECTIVE

A pilot study to estimate the prevalence of osteopenia and osteoporosis in postmenopausal Saudi women.

METHODS

Lumbar spine bone density was measured in 830 postmenopausal Saudi women 50-80 years of age (average 59 years), using dual x-ray absorptiometry (DXA) at the King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between 1989 and 1999.

RESULTS

The results of the bone mineral density (BMD) in gm/cm2 were compared to the peak bone density (PBD) in healthy young women (T-score). Based on the definition of World Health Organization (WHO), the T-score value was considered for analysis. Accordingly, 248 (29.9%) subjects showed normal result, mean BMD of 1.117 +/- 0.13 and T-score of -0.66 SD; while 254 (30.6%) subjects showed osteopenia, mean BMD of 0.983 +/- 0.11 and T-score of -2.4 SD and 328(39.5%) subject showed osteoporosis, mean BMD of 0.767 +/- 0.11 and T-score of -3.4 SD. When the 830 subjects were analyzed by decades, there were 42.3% normal, 33.4% osteopenia and 24.3% osteoporosis in age 50-59 years; 11% normal, 27% with osteopenia and 62% with osteoporosis in age 60-69 years while in older age 70-79 years only 4.6% had normal BMD, 21.5% had osteopenia and 73.8% had osteoporosis.

CONCLUSION

Osteopenia and osteoporosis are common among postmenopausal Saudi women and should be considered as a matter of public health. Bone densitometry should be used to assess the severity of bone loss, identify those who need therapy and for follow up and early diagnosis of those with osteopenia in order to institute proper therapy and avoid future osteoporosis.

摘要

目的

一项初步研究,旨在估算沙特绝经后女性中骨质减少和骨质疏松症的患病率。

方法

1989年至1999年期间,在沙特阿拉伯利雅得的哈立德国王大学医院,使用双能X线吸收法(DXA)对830名年龄在50至80岁(平均59岁)的沙特绝经后女性进行腰椎骨密度测量。

结果

将以克/平方厘米为单位的骨矿物质密度(BMD)结果与健康年轻女性的峰值骨密度(PBD)(T值)进行比较。根据世界卫生组织(WHO)的定义,考虑T值进行分析。据此,248名(29.9%)受试者结果正常,平均BMD为1.117±0.13,T值为-0.66标准差;254名(30.6%)受试者显示骨质减少,平均BMD为0.983±0.11,T值为-2.4标准差;328名(39.5%)受试者显示骨质疏松症,平均BMD为0.767±0.11,T值为-3.4标准差。当按年龄段对这830名受试者进行分析时,50至59岁年龄段中42.3%正常、33.4%骨质减少、24.3%骨质疏松症;60至69岁年龄段中11%正常、27%骨质减少、62%骨质疏松症;而在70至79岁的老年组中,只有4.6%骨密度正常,21.5%骨质减少,73.8%骨质疏松症。

结论

骨质减少和骨质疏松症在沙特绝经后女性中很常见,应被视为一个公共卫生问题。骨密度测定应用于评估骨质流失的严重程度,识别需要治疗的人群,并对骨质减少者进行随访和早期诊断,以便实施适当治疗并避免未来发生骨质疏松症。

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