van Trijp M J, Grobbee D E, Hoes A W, Bots M L
Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Heidelberglaan 100, 3584 CX Utrecht.
Ned Tijdschr Geneeskd. 2003 Jul 26;147(30):1456-9.
To find an answer in the literature to the question of which blood pressure parameter (systolic, diastolic or pulse pressure) best predicts cardiovascular disease and whether the magnitude of the association of the parameter varies with age.
Structured literature review.
Pubmed was searched for prospective cohort studies concerning the predictive power of two or more blood-pressure components (in particular pulse pressure).
Seven relevant articles were found. Systolic blood pressure was found to be a powerful predictor for cardiovascular disease at every age, while pulse pressure was found to be the weakest predictor. The predictive power of diastolic pressure was intermediate, and decreased with age whereas that of pulse pressure increased with age.
Systolic blood pressure was the best predictor for cardiovascular disease, whereas the role of diastolic pressure appeared to be limited.
在文献中寻找以下问题的答案：哪种血压参数（收缩压、舒张压或脉压）最能预测心血管疾病，以及该参数的关联强度是否随年龄而变化。
结构化文献综述。
在PubMed上搜索关于两种或更多血压成分（特别是脉压）预测能力的前瞻性队列研究。
找到7篇相关文章。发现收缩压在各个年龄段都是心血管疾病的有力预测指标，而脉压是最弱的预测指标。舒张压的预测能力处于中间水平，且随年龄下降，而脉压的预测能力随年龄增加。
收缩压是心血管疾病的最佳预测指标，而舒张压的作用似乎有限。
