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[需治疗人数——NNT]

[NNT--numbers needed to treat].

作者信息

Netzer Doron, Berkovitzs Eldar, Reis Shmuel, Weinberger Tuvia

机构信息

Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa.

出版信息

Harefuah. 2003 Jul;142(7):541-3, 565.

Abstract

Number needed to treat--NNT--is a bridging tool between statistical results from clinical trials and the physician daily work. This number represents the number of patients we need to treat with the experimental therapy in order to prevent one of them from developing the bad outcome. The concept is a useful measure of the clinical effort our patient and we must expend in order to help them avoid bad outcomes to their illness. For example, the NNT for antibiotic treatment of otitis media is 8, which means that we have to treat eight children with antibiotic and only one out of the eight will benefit the treatment. In a medical world that uses the Evidence Based Medicine as essential tool, we believe that the NNT is an important tool and very efficient for choosing the best treatment method.

摘要

需治疗人数(NNT)是临床试验统计结果与医生日常工作之间的桥梁工具。这个数字代表了我们需要用实验性疗法治疗的患者数量,以便防止其中一人出现不良后果。这个概念是衡量我们和患者为帮助他们避免疾病不良后果而必须付出的临床努力的有用指标。例如,中耳炎抗生素治疗的NNT为8,这意味着我们必须用抗生素治疗8名儿童,其中只有1名将从治疗中受益。在一个将循证医学作为基本工具的医学领域,我们认为NNT是选择最佳治疗方法的重要且非常有效的工具。

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