Linna O, Kokkonen J, Lahtela P, Tammela O
Department of Paediatrics, University of Oulu, Finland.
Acta Paediatr. 1992 Dec;81(12):1013-6. doi: 10.1111/j.1651-2227.1992.tb12165.x.
Forty children treated in our hospital for generalized infantile eczema were re-examined at 11-13 years of age. In 7 (18%) children the eczema had disappeared and in 26 (65%) it had become less severe. Unrelated to dermatological status or gender, allergic rhinitis was diagnosed in 31 (78%) and asthma in 21 (53%) children. Only 8 children continued without either of these two conditions. All 32 children with allergic rhinitis and/or asthma showed at least one positive skin test reaction in a test panel of 11 common inhalant and food allergens compared with only 4 of 8 children without either allergic rhinitis or asthma (p < 0.001). Our results showed an improvement of dermatological status in most children with generalized infantile eczema but there was a high risk of a concomitant respiratory allergy and development of allergic rhinitis or asthma.
在我院接受治疗的40例泛发性婴儿湿疹患儿在11至13岁时接受了复查。7例（18%）患儿的湿疹已消失，26例（65%）患儿的湿疹病情减轻。与皮肤状况或性别无关，31例（78%）患儿被诊断为过敏性鼻炎，21例（53%）患儿被诊断为哮喘。只有8名儿童没有这两种疾病。在11种常见吸入性和食物过敏原的检测组中，所有32例患有过敏性鼻炎和/或哮喘的儿童至少有一项皮肤试验呈阳性反应，而8例既没有过敏性鼻炎也没有哮喘的儿童中只有4例呈阳性反应（p<0.001）。我们的结果显示，大多数泛发性婴儿湿疹患儿的皮肤状况有所改善，但同时存在呼吸道过敏以及发生过敏性鼻炎或哮喘的风险很高。
