Salle B L, Braillon P, Glorieux F H, Brunet J, Cavero E, Meunier P J
Department of Neonatology, Edouard Herriot Hospital, Lyon, France.
Acta Paediatr. 1992 Dec;81(12):953-8. doi: 10.1111/j.1651-2227.1992.tb12152.x.
Dual energy X-ray absorptiometry (DXA), a non-invasive method for measuring small amounts of mineral, was used to assess the bone mineral content (BMC) and bone mineral density (BMD) of the lumbar spine (5 vertebrae) in 57 newborns (on day 1-2) and 22 infants (1-24 months of age). A modified high-resolution program (Hologic) allowed us to assess BMC and BMD with a precision higher than 2.4% and 1.5%, respectively. In newborns, BMC and BMD correlated positively with birth weight, body area, length and gestational age: r = 0.73, 0.71, 0.63 and 0.60, respectively, for BMC; and r = 0.59, 0.58, 0.54 and 0.53, respectively, for BMD. In infants, both BMC and BMD were highly correlated with weight, age, length and body area over two years (r = 0.94 or better in each instance). The data provide normal values for lumbar spine BMC and BMD in newborns (gestational age 31-40) and infants up to two years of age; DXA appears to be an excellent and safe tool for pediatric bone mineral measurements.
双能X线吸收法（DXA）是一种测量少量矿物质的非侵入性方法，用于评估57名新生儿（出生后1 - 2天）和22名婴儿（1 - 24个月龄）腰椎（5个椎体）的骨矿物质含量（BMC）和骨矿物质密度（BMD）。一种改良的高分辨率程序（Hologic）使我们能够分别以高于2.4%和1.5%的精度评估BMC和BMD。在新生儿中，BMC和BMD与出生体重、体表面积、身长和胎龄呈正相关：BMC的相关系数分别为r = 0.73、0.71、0.63和0.60；BMD的相关系数分别为r = 0.59、0.58、0.54和0.53。在婴儿中，BMC和BMD在两年内均与体重、年龄、身长和体表面积高度相关（每种情况的r = 0.94或更高）。这些数据提供了新生儿（胎龄31 - 40周）和两岁以下婴儿腰椎BMC和BMD的正常值；DXA似乎是用于儿科骨矿物质测量的一种出色且安全的工具。
