胰腺癌的转基因模型 - Suppr

Transgenic models of pancreatic cancer.

作者信息

Lowy Andrew M

机构信息

Division of Surgical Oncology, University of Cincinnati College of Medicine, 234 Goodman Street, Cincinnati, OH 45219-0772, USA.

出版信息

Int J Gastrointest Cancer. 2003;33(1):71-8. doi: 10.1385/IJGC:33:1:71.

DOI:10.1385/IJGC:33:1:71

PMID:12909739

Abstract

摘要

相似文献

Transgenic models of pancreatic cancer.

Int J Gastrointest Cancer. 2003;33(1):71-8. doi: 10.1385/IJGC:33:1:71.

Animal models of exocrine pancreatic cancer.

Int J Colorectal Dis. 2000 Jun;15(3):136-43. doi: 10.1007/s003840000229.

Evaluation and utilization of transgenic animal models in studies of pancreatic cancer. Pancreas Cancer Working Group.

Pancreas. 1987;2(4):470-2.

Models of Exocrine Pancreatic Neoplasms in Transgenic Mice.

Comp Med. 2004 Feb;54(1):18-21.

Gene alterations in rodent and human tumors of the exocrine and endocrine pancreas.

Prog Clin Biol Res. 1992;376:223-43.

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

Cancer Res. 2006 Jan 1;66(1):95-106. doi: 10.1158/0008-5472.CAN-05-2168.

Experimental animal models in pancreatic carcinogenesis: lessons for human pancreatic cancer.

Dig Dis. 2001;19(1):24-31. doi: 10.1159/000050650.

Recent results in animal models of pancreatic carcinoma: histogenesis of tumors.

Yale J Biol Med. 1992 Sep-Oct;65(5):457-64; discussion 465-9.

Animal models of spontaneous pancreatic neuroendocrine tumors.

Mol Cell Endocrinol. 2016 Feb 5;421:60-7. doi: 10.1016/j.mce.2015.08.004. Epub 2015 Aug 7.

Endocrine Tumors of the Pancreas in Transgenic Mice.

Comp Med. 2004 Feb;54(1):21-2.

引用本文的文献

Expression of DNA-repair proteins and their significance in pancreatic cancer and non-cancerous pancreatic tissues of Sprague-Dawley rats.

World J Surg Oncol. 2014 Feb 6;12:32. doi: 10.1186/1477-7819-12-32.

Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer.

Histol Histopathol. 2007 Jun;22(6):661-76. doi: 10.14670/HH-22.661.

Characterization of pancreatic lesions from MT-tgf alpha, Ela-myc and MT-tgf alpha/Ela-myc single and double transgenic mice.

J Carcinog. 2006 Jul 5;5:19. doi: 10.1186/1477-3163-5-19.

本文引用的文献

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.

Nat Genet. 2002 Sep;32(1):128-34. doi: 10.1038/ng959. Epub 2002 Aug 19.

Cancer statistics, 2002.

CA Cancer J Clin. 2002 Jan-Feb;52(1):23-47. doi: 10.3322/canjclin.52.1.23.

Experimental animal models in pancreatic carcinogenesis: lessons for human pancreatic cancer.

Dig Dis. 2001;19(1):24-31. doi: 10.1159/000050650.

The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice.

Gastroenterology. 2001 Jun;120(7):1720-8. doi: 10.1053/gast.2001.24846.

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129.

Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators.

J Gastrointest Surg. 2000 Nov-Dec;4(6):567-79. doi: 10.1016/s1091-255x(00)80105-5.

Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.

Cancer Res. 2000 Jan 15;60(2):409-16.

Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice.

Gastroenterology. 1998 Nov;115(5):1254-62. doi: 10.1016/s0016-5085(98)70098-8.

Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants.

J Clin Invest. 1998 Jul 15;102(2):294-301. doi: 10.1172/JCI2769.

A regulatory system for target gene expression.

Front Biosci. 1998 Jan 1;3:c1-7. doi: 10.2741/a258.

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Transgenic models of pancreatic cancer.

作者信息

Lowy Andrew M

机构信息

Division of Surgical Oncology, University of Cincinnati College of Medicine, 234 Goodman Street, Cincinnati, OH 45219-0772, USA.

出版信息

Int J Gastrointest Cancer. 2003;33(1):71-8. doi: 10.1385/IJGC:33:1:71.

DOI:10.1385/IJGC:33:1:71

PMID:12909739

Abstract

摘要

相似文献

Transgenic models of pancreatic cancer.

Int J Gastrointest Cancer. 2003;33(1):71-8. doi: 10.1385/IJGC:33:1:71.

Animal models of exocrine pancreatic cancer.

Int J Colorectal Dis. 2000 Jun;15(3):136-43. doi: 10.1007/s003840000229.

Evaluation and utilization of transgenic animal models in studies of pancreatic cancer. Pancreas Cancer Working Group.

Pancreas. 1987;2(4):470-2.

Models of Exocrine Pancreatic Neoplasms in Transgenic Mice.

Comp Med. 2004 Feb;54(1):18-21.

Gene alterations in rodent and human tumors of the exocrine and endocrine pancreas.

Prog Clin Biol Res. 1992;376:223-43.

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

Cancer Res. 2006 Jan 1;66(1):95-106. doi: 10.1158/0008-5472.CAN-05-2168.

Experimental animal models in pancreatic carcinogenesis: lessons for human pancreatic cancer.

Dig Dis. 2001;19(1):24-31. doi: 10.1159/000050650.

Recent results in animal models of pancreatic carcinoma: histogenesis of tumors.

Yale J Biol Med. 1992 Sep-Oct;65(5):457-64; discussion 465-9.

Animal models of spontaneous pancreatic neuroendocrine tumors.

Mol Cell Endocrinol. 2016 Feb 5;421:60-7. doi: 10.1016/j.mce.2015.08.004. Epub 2015 Aug 7.

Endocrine Tumors of the Pancreas in Transgenic Mice.

Comp Med. 2004 Feb;54(1):21-2.

引用本文的文献

Expression of DNA-repair proteins and their significance in pancreatic cancer and non-cancerous pancreatic tissues of Sprague-Dawley rats.

World J Surg Oncol. 2014 Feb 6;12:32. doi: 10.1186/1477-7819-12-32.

Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer.

Histol Histopathol. 2007 Jun;22(6):661-76. doi: 10.14670/HH-22.661.

Characterization of pancreatic lesions from MT-tgf alpha, Ela-myc and MT-tgf alpha/Ela-myc single and double transgenic mice.

J Carcinog. 2006 Jul 5;5:19. doi: 10.1186/1477-3163-5-19.

本文引用的文献

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.

Nat Genet. 2002 Sep;32(1):128-34. doi: 10.1038/ng959. Epub 2002 Aug 19.

Cancer statistics, 2002.

CA Cancer J Clin. 2002 Jan-Feb;52(1):23-47. doi: 10.3322/canjclin.52.1.23.

Experimental animal models in pancreatic carcinogenesis: lessons for human pancreatic cancer.

Dig Dis. 2001;19(1):24-31. doi: 10.1159/000050650.

The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice.

Gastroenterology. 2001 Jun;120(7):1720-8. doi: 10.1053/gast.2001.24846.

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129.

Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators.

J Gastrointest Surg. 2000 Nov-Dec;4(6):567-79. doi: 10.1016/s1091-255x(00)80105-5.

Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.

Cancer Res. 2000 Jan 15;60(2):409-16.

Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice.

Gastroenterology. 1998 Nov;115(5):1254-62. doi: 10.1016/s0016-5085(98)70098-8.

Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants.

J Clin Invest. 1998 Jul 15;102(2):294-301. doi: 10.1172/JCI2769.

A regulatory system for target gene expression.

Front Biosci. 1998 Jan 1;3:c1-7. doi: 10.2741/a258.

Transgenic models of pancreatic cancer.

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Transgenic models of pancreatic cancer.

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